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CAS RN: 62893-19-0 | Product Number: C2768
Cefoperazone
×
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2768 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__2__7N__9O__8S__2 = 645.67 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 62893-19-0 |
| Related CAS RN
|
62893-20-3 |
| Reaxys Registry Number | 6050252 |
| PubChem Substance ID | 253659769 |
| Merck Index (14) | 1930 |
| MDL Number | MFCD00865067 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 173 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | XI0373900 |
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Cefoperazone: A Third Generation Semisynthetic Cephalosporin Antibiotic with Activity against Pseudomonas aeruginosa
Cefoperazone is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266]. It has a broad spectrum of antibacterial activity gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria except enterococci. Unlike other cephalosporins, cefoperazone is considerably excreted into the bile.
References
- Cefoperazone: A review of its in vitro antimicrobial activity, pharmacological properties and therapeutic efficacy
- Pharmacokinetics of cefoperazone: a review
- Cefoperazone: a review of its antimicrobial spectrum, beta-lactamase stability, enzyme inhibition, and other in vitro characteristics
- Reversed-phase HPLC determination of antibiotics of the cephalosporin series in biological objects (review)
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