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CAS RN: 1665-48-1 | Product Number: M2578
Metaxalone
Purity: >98.0%(GC)
Synonyms:
- 5-(3,5-Dimethylphenoxymethyl)-2-oxazolidinone
- 5-[(3,5-Xylyloxy)methyl]-2-oxazolidinone
Product Documents:
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| Product Number | M2578 |
Purity / Analysis Method
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__5NO__3 = 221.26 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1665-48-1 |
| Reaxys Registry Number | 884592 |
| PubChem Substance ID | 253662077 |
| MDL Number | MFCD00867700 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 122.0 to 126.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 124 °C |
| Boiling Point | 225 °C/1.5 mmHg |
| Solubility in water | Insoluble |
| Degree of solubility in water | 91 mg/l 25 °C |
| Solubility (soluble in) | Ethanol, Methanol |
| Solubility (insoluble in) | Ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | RQ3850000 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Metaxalone: A Muscle Relaxant
Metaxalone is a muscle relaxant which is used to relieve pain caused by strains, sprains and other muscle injuries with no defined cellular mechanism of action. Its efficacy has been considered to be due to general central nervous system depression. (The product is for research purpose only.)
References
- Commonly used muscle relaxant therapies for acute low back pain: a review of carisoprodol, cyclobenzaprine hydrochloride, and metaxalone (a review)
- Metaxalone (Skelaxin®)-related death
- Quantification of Metaxalone in Human Plasma by Liquid Chromatography Coupled to Tandem Mass Spectrometry
- New stability-indicating RP-HPLC method for determination of diclofenac [D3748] potassium and metaxalone from their combined dosage form
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