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7-Aminodesacetoxycephalosporanic Acid
(CAS Number:22252-43-3 Product Number:A2075)

Structure

7-Aminodesacetoxycephalosporanic Acid
Synonym 7-ADCA

General Information

Product Number A2075

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature
M.F. / M.W. C8H10N2O3S=214.24
CAS Number 22252-43-3
Related CAS Number
MDL Number MFCD00151456
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 95.0 %
Specific rotation [a]20/D +100.0 to +107.0 deg(C=1, 1mol/L HCl)

Data of Reference

mp 242°C(dec.)(lit.)

References

Reaxys-RN 615092
PubChem SID 87560170

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H317
  • :May cause an allergic skin reaction.
  • H334
  • :May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statements
  • P261
  • :Avoid breathing dust, fume, mist, vapors or spray.
  • P272
  • :Contaminated work clothing must not be allowed out of the workplace.
  • P280
  • :Wear protective gloves.
  • P284
  • :Wear respiratory protection.
  • P302+P352+P333+P313+P363
  • :If on skin: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice or attention. Wash contaminated clothing before reuse.
  • P304+P340+P342+P311
  • :If inhaled: If breathing is difficult, remove person to fresh air and keep comfortable for breathing. If experiencing respiratory symptoms: Call a poison center or doctor.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Transport Information

HS Number 2941.90.5000

Application

7-Aminodesacetoxycephalosporanic Acid (7-ADCA): A Starting Compound for Semisynthetic Cephalosporin Antibiotics

7-Aminodesacetoxycephalosporanic acid (7-ADCA) is conventionally produced from penicillin. It is used as a starting compound for semisynthetic cephalosporin antibiotics. Differences in side chain structure at the 7-position directly affect their antibiotic activity.

References

PubMed Literature

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