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Published TCIMAIL newest issue No.199
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CAS RN: 5058-13-9 | Product Number: C3479
Columbianadin
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Purity: >98.0%(HPLC)
Synonyms:
- (S)-2-(2-Oxo-8,9-dihydro-2H-furo[2,3-h]chromen-8-yl)propan-2-yl (Z)-2-Methylbut-2-enoate
- (Z)-2-Methylbut-2-enoic Acid (S)-2-(2-Oxo-8,9-dihydro-2H-furo[2,3-h]chromen-8-yl)propan-2-yl Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€218.00
|
Contact Us | 6 |
|
| 100MG |
€720.00
|
Contact Us | 12 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | C3479 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__0O__5 = 328.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 5058-13-9 |
| PubChem Substance ID | 354335572 |
| MDL Number | MFCD07781426 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Carbon) | 68.00 to 71.00 % |
| Melting point | 117.0 to 121.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 119 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2932209090 |
Application
Columbianadin: a coumarin-type natural product with strong anti-inflammatory and analgesic activities
Columbianadin (or columbianetin) is one of the main bioactive coumarin-type constituents of the roots of Angelica decursiva. Reportedly, columbianadin possess strong anti-inflammatory and analgesic activities. (The product is for research purpose only.)
References
- Anti-inflammatory and analgesic activities from roots of Angelica pubescens
- Biotransformation of columbianadin by rat hepatic microsomes and inhibition of biotransformation products on NO production in RAW 264.7 cells in vitro
- Inhibition of airway inflammation by the roots of Angelica decursiva and its constituent, columbianadin (a review)
- Comparative study of roots of Angelica sinensis and related umbelliferous drugs by thin layer chromatography, high-performance liquid chromatography, and liquid chromatography - mass spectrometry
- Vibrational spectroscopic studies on the natural product, columbianadin
PubMed Literature
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