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Published TCIMAIL newest issue No.199
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CAS RN: 15307-79-6 | Product Number: D2508
Diclofenac Sodium Salt
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Purity: >98.0%(HPLC)(N)
Synonyms:
- 2-(2,6-Dichloroanilino)phenylacetic Acid Sodium Salt
- Sodium 2-(2,6-Dichloroanilino)phenylacetate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25G |
€64.00
|
29 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D2508 |
Purity / Analysis Method 
|
>98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__1__4H__1__0Cl__2NNaO__2 = 318.13 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 15307-79-6 |
| Related CAS RN
|
15307-86-5 |
| Reaxys Registry Number | 3581138 |
| PubChem Substance ID | 87568933 |
| Merck Index (14) | 3081 |
| MDL Number | MFCD00082251 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Solubility in Methanol | almost transparency |
Properties (reference)
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 239-346-4 |
| RTECS# | AG6330000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2922498590 |
Application
DNA aptamer research
Reference
- ssDNA aptamers that recognize diclofenac and 2-anilinophenylacetic acid
Application
Diclofenac Sodium Salt: A Non-Selective Non-Steroidal Anti-Inflammatory Drug (NSAID)
Diclofenac sodium salt is a sodium salt of diclofenac [D3748] which is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. It is a non-selective cyclooxygenase (COX) inhibitor. COX directs the formation of several key mediators of inflammation called prostaglandins. Thus, diclofenac sodium salt reduces the synthesis of prostaglandins. Diclofenac sodium salt is often used as a delayed-release dosage form of diclofenac. In addition, diclofenac sodium salt has been reportedly found to possess antibacterial activity. (The product is for research purpose only.)
References
- Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy (a review)
- On the use of the Weibull function for the discernment of drug release mechanisms
- Formulation optimization of controlled release diclofenac sodium microspheres using factorial design
- Preparation and characterization of a novel pH-sensitive chitosan-g-poly (acrylic acid)/attapulgite/sodium alginate composite hydrogel bead for controlled release of diclofenac sodium
- The anti-inflammatory non-antibiotic helper compound diclofenac: an antibacterial drug target (a review)
- Diclofenac sodium (a review on the preparation, physical properties, stability, toxicity, and analytical methods for detection of diclofenac sodium)
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