Published TCIMAIL newest issue No.201
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 15307-86-5 | Product Number: D3748
2-(2,6-Dichloroanilino)phenylacetic Acid
×
Purity: >98.0%(GC)(T)
Synonyms:
- Diclofenac
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25G |
€ 70,00
|
13 | ≥100 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | D3748 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__4H__1__1Cl__2NO__2 = 296.15 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 15307-86-5 |
| Reaxys Registry Number | 2146636 |
| PubChem Substance ID | 87561265 |
| Merck Index (14) | 3081 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 158 °C(dec.) |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| EC Number | 239-348-5 |
| RTECS# | AG6310000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2922498590 |
Application
DNA aptamer research
Reference
- ssDNA aptamers that recognize diclofenac and 2-anilinophenylacetic acid
Application
Diclofenac: A Non-Selective Non-Steroidal Anti-Inflammatory Drug (NSAID)
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with strong analgesic activity. It is a non-selective cyclooxygenase (COX) inhibitor. COX directs the formation of several key mediators of inflammation called prostaglandins. Thus, diclofenac reduces the synthesis of prostaglandins. Diclofenac is metabolized principally by CYP2C9. Diclofenac is often used as a potassium salt (immediate-release) or sodium salt [D2508] (delayed-release). In addition, diclofenac and its metabolites are reportedly often detected in waste waters, since diclofenac is a common pharmaceutical agent. (The product is for research purpose only.)
References
- Cyclooxygenase-1 and Cyclooxygenase-2 Selectivity of Widely Used Nonsteroidal Anti-Inflammatory Drugs
- Diclofenac sodium. A reappraisal of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy (a review)
- Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy (a review)
- The metabolism of diclofenac - enzymology and toxicology perspectives (a review)
- Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry
- Simultaneous determination of aceclofenac and three of its metabolites in human plasma by high-performance liquid chromatography
PubMed Literature
Documents
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
Enter TCI Product Number
Enter KISHIDA Product Number
4-5 alphanumeric characters before the hyphen
7 alphanumeric characters
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
• The requested SDS is not available.
Specifications
The requested specifications are not available.
Please Contact Us for more information.
The requested specifications are not available.
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
• Please check that the lot number you have entered is correct. It is 4-5 alphanumeric characters before the hyphen. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
• If your information is correct and you are still not able to view the requested certificates, Please Contact Us for more information.
• Please check that the lot number you have entered is correct. It is 7 alphanumeric characters. In particular, please check O (letter) or 0 (number) and I (letter) or 1 (number).
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Incorrect Lot Number. Please input only the 7 alphanumeric characters.
The requested analytical chart is not available. Sorry for the inconvenience.