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CAS RN: 5053-08-7 | Product Number: F1211
Fenspiride Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€27.00
|
1 | 1 |
|
|
| 5G |
€102.00
|
1 | 6 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | F1211 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__0N__2O__2·HCl = 296.80 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 5053-08-7 |
| Related CAS RN
|
5053-06-5 |
| Reaxys Registry Number | 9017699 |
| PubChem Substance ID | 468591848 |
| Merck Index (14) | 3999 |
| MDL Number | MFCD00133315 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 240 °C(dec.) |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 225-752-9 |
| RTECS# | RO0375000 |
Transport Information:
| HS Number | 2934999090 |
Application
Fenspiride Hydrochloride: An Antiinflammatory and Bronchodilator Agent
Fenspiride hydrochloride is an antiinflammatory and bronchodilator agent with low cyclooxygenase (COX) inhibitory activity. It has been used for the treatment of certain respiratory diseases. (The product is for research purpose only.)
References
- Blockade by fenspiride of endotoxin-induced neutrophil migration in the rat
- Fenspiride: an anti-inflammatory drug with potential benefits in the treatment of endotoxemia
- Antitussive and antibronchoconstriction actions of fenspiride in guinea pigs
- Detection of fenspiride and identification of in vivo metabolites in horse body fluids by capillary gas chromatography-mass spectrometry: administration, biotransformation and urinary excretion after a single oral dose
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