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CAS RN: 26807-65-8 | Product Number: I0730

Indapamide

Thumbnail of Indapamide
  • Chemical Structure of Indapamide
Chemical Structure of Indapamide
× Indapamide

Purity: >97.0%(T)(HPLC)
Synonyms:
  • 1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
Product Documents:
SDS | Specifications | C of A & Other Certificates | Analytical Charts

General Information | Specifications & Properties | Safety & Regulations | Applications & Literature

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Product Number I0730
Purity / Analysis Method >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__6H__1__6ClN__3O__3S = 365.83 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 26807-65-8
Reaxys Registry Number 1604026
PubChem Substance ID 87561081
Merck Index (14) 4935
MDL Number

MFCD00079375
Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Neutralization titration) min. 97.0 %
Melting point 167.0 to 173.0 °C
Properties (reference)
Melting Point 170 °C
GHS
Related Laws:
EC Number 248-012-7
RTECS# CV2451200
Transport Information:
HS Number 2935909099
Application
Indapamide: A Thiazide-Like Antihypertensive/Diuretic Agent

Indapamide is a thiazide-like antihypertensive/diuretic agent. Incidentally, thiazide diuretic agents include hydrochlorothiazide [H1274] and xipamide. Indapamide molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. Indapamide have a mild diuretic activity and a peripheral vasodilatory effect. The mechanism of action has not been completely elucidated, but indapamide affects the distal convoluted tubules, where they inhibit Na+/Cl- cotransport in the luminal membrane of tubule cells. Thus, reabsorption of NaCl and water is inhibited. (The product is for research purpose only.)

References


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