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Published TCIMAIL newest issue No.199
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CAS RN: 23672-07-3 | Product Number: I0821
(S)-(-)-Sulpiride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
- Levosulpiride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€65.00
|
1 | 21 |
|
| 25G |
€275.00
|
1 | 3 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | I0821 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__3N__3O__4S = 341.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 23672-07-3 |
| Reaxys Registry Number | 3563418 |
| PubChem Substance ID | 135726922 |
| Merck Index (14) | 8989 |
| MDL Number | MFCD00055220 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 185.0 to 189.0 °C |
| Specific rotation [a]20/D | -67.0 to -71.0 deg(C=3, DMF) |
Properties (reference)
| Melting Point | 187 °C |
| Specific Rotation | -69° (C=3,DMF) |
| Solubility (soluble in) | Dimethylformamide |
GHS
Related Laws:
| RTECS# | BZ3400100 |
Transport Information:
| HS Number | 2935909099 |
Application
(S)-(-)-Sulpiride: A Dopamine D2 Receptor Antagonist
(S)-(-)-Sulpiride (or levosulpiride) is the active enantiomer of (±)-sulpiride [S0501], and a substituted benzamide-type atypical antipsychotic having the properties of dopamine D2 receptor antagonist. (The product is for research purpose only.)
References
- The effects of S(-) and R(+) sulpiride, metoclopramide, cisapride and domperidone on the small intestine suggest DA2-receptors are involved in the control of small intestinal transit time in rats
- Disposition of enantiomers of sulpiride in humans and rats
- Pharmacotoxicological aspects of levosulpiride (a review)
- Levosulpiride: A review of its clinical use in psychiatry (a review)
- Hydrophilic interaction liquid chromatography-tandem mass spectrometry for the determination of levosulpiride in human plasma
- Spectrophotometric estimation of levosulpiride in bulk drug and formulations
PubMed Literature
Product Articles
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