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CAS RN: 5041-81-6 | Product Number: I1144
Isoliquiritin
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Purity: >98.0%(HPLC)
Synonyms:
- 2',4,4'-Trihydroxychalcone 4-Glucoside
- Isoliquiritoside
- 4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-Glucopyranoside
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
€279.00
|
Contact Us | 16 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | I1144 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2O__9 = 418.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 5041-81-6 |
| Reaxys Registry Number | 59159 |
| PubChem Substance ID | 468592122 |
| MDL Number | MFCD00272145 |
Specifications
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 195.0 to 199.0 °C |
| Specific rotation [a]20/D | -67.0 to -71.0 deg(C=1, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 198 °C |
| Maximum Absorption Wavelength | 361 nm (MeOH) |
GHS
Related Laws:
Transport Information:
| HS Number | 2938909090 |
Application
Isoliquiritigenin: A Bioactive Component of the Roots of Glycyrrhiza uralensis
Isoliquiritin is a bioactive phenylpropanoid isolated from the roots of Glycyrrhiza uralensis which has been used as a traditional Chinese medicine for the treatment of inflammatory diseases. It has been reported that isoliquiritin has multiple biological activities, including antioxidant, anti-inflammatory, anti-angiogenesis, anti-tube formation, and antidepressant-like effects. (The product is for research purpose only.)
References
- Isoliquiritin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-κB in RAW 264.7 macrophages
- Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro
- Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice
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