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CAS RN: 88678-31-3 | Product Number: L0301
Liranaftate
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Purity: >98.0%(HPLC)
Synonyms:
- O-(5,6,7,8-Tetrahydronaphthalen-2-yl) (6-Methoxypyridin-2-yl)(methyl)carbamothioate
- (6-Methoxypyridin-2-yl)(methyl)carbamothioic Acid O-(5,6,7,8-Tetrahydronaphthalen-2-yl) Ester
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 50MG |
€76.00
|
1 | 6 |
|
| 250MG |
€265.00
|
Contact Us | 6 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | L0301 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__0N__2O__2S = 328.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 88678-31-3 |
| Reaxys Registry Number | 12615149 |
| PubChem Substance ID | 354335085 |
| Merck Index (14) | 5515 |
| MDL Number | MFCD00865576 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 8.00 to 9.00 % |
| Melting point | 97.0 to 101.0 °C |
Properties (reference)
| Melting Point | 99 °C |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Acetone, dichloromethane |
| Solubility (slightly sol. in) | Diethyl ether |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P261 : Avoid breathing dust. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | FD3890000 |
Transport Information:
| HS Number | 2933399990 |
Application
Liranaftate: A Synthetic Thiocarbamate Antifungal Reagent
Liranaftate (piritetrate or M-732) is a chemical synthetic antifungal reagent, belonging chemically to the thiocarbamates. Although the exact mechanism of action is not entirely known, liranaftate would inhibit sterol biosynthesis at the level of squalene epoxidase which is an important enzyme in the biosynthetic pathway of the fungal membrane. Similar antifungal reagent includes tolnaftate [T3059]. (The product is for research purpose only.)
References
- Inhibitory effect of a new mycotic agent, piritetrate on ergosterol biosynthesis in pathogenic fungi
- In vitro and in vivo activities of piritetrate (M-732), a new antidermatophytic thiocarbamate
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