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CAS RN: 13614-98-7 | Product Number: M2288
Minocycline Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
104,00 €
|
4 | ≥80 |
|
|
| 5G |
330,00 €
|
1 | ≥60 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | M2288 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__3H__2__7N__3O__7·HCl = 493.94 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 13614-98-7 |
| Related CAS RN
|
10118-90-8 |
| Reaxys Registry Number | 4836328 |
| PubChem Substance ID | 160871228 |
| Merck Index (14) | 6202 |
| MDL Number | MFCD00083669 |
Specifications
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | -170 to -180 deg(C=0.5、0.1mol/L HCl) |
| Water | 4.3 to 8.0 % |
Properties (reference)
| Specific Rotation | -175° (C=0.5,0.1mL/L HCl) |
| Solubility in water | Slightly soluble |
| Solubility (soluble in) | Methanol, Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H362 : May cause harm to breast-fed children. H317 : May cause an allergic skin reaction. |
| Precautionary Statements | P263 : Avoid contact during pregnancy and while nursing. P260 : Do not breathe dust. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. |
Related Laws:
| EC Number | 237-099-7 |
| RTECS# | QI7630500 |
Transport Information:
| HS Number | 2941300000 |
Application
Gingipain inhibitor
Minocycline has been reported to inhibit gingipains, arginine-specific gingipains (HRgpA and RgpB), and lysine-specific gingipain (Kgp) from Porphyromonas gingivalis.1) (The product is for research purpose only.)
Reference
- 1) Inhibition of Trypsin-Like Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis by Tetracycline and Its Analogues
- The broad-spectrum activity and efficacy of catheters coated with minocycline and rifampin
- Neuroprotective and anti-human immunodeficiency virus activity of minocycline
- Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
- Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease
- A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window
- Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
Application
Studies on Antibiotic Activity
References
Application
Neuroprotective Studies
References
PubMed Literature
Documents
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Safety Data Sheet (SDS)
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Specifications
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