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CAS RN: 1041434-82-5 | Product Number: P2892
Peramivir Trihydrate
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Purity: >97.0%(T)(HPLC)
Synonyms:
- BCX-1812 Trihydrate
- (1S,2S,3R,4R)-3-[(S)-1-Acetamido-2-ethylbutyl]-4-guanidino-2-hydroxycyclopentane-1-carboxylic Acid Trihydrate
- (1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic Acid Trihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
63,00 €
|
1 | ≥40 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P2892 |
Purity / Analysis Method 
|
>97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__5H__2__8N__4O__4·3H__2O = 382.46 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 1041434-82-5 |
| Reaxys Registry Number | 18582192 |
| PubChem Substance ID | 468592766 |
| MDL Number | MFCD22417093 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Volumetric Analysis) | min. 97.0 % |
| Specific rotation | -124 to -132 deg (C=1, water) |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Slightly soluble |
| Solubility (insoluble in) | Dimethylformamide |
GHS
Related Laws:
Transport Information:
| HS Number | 2925290090 |
Application
Peramivir: An Inhibitor of Influenza Virus Neuraminidase
Peramivir (BCX-1812, RWJ-270201) is an inhibitor of influenza virus neuraminidase, which is an enzyme that releases viral particles from the plasma membrane of infected cells. (The product is for research purpose only.)
References
- Bcx-1812 (rwj-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design
- Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses
- Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance (a review)
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