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CAS RN: 6106-46-3 | Product Number: S0230
Scopolamine Methyl Nitrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Methscopolamine Nitrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€96.00
|
2 | 9 |
|
|
| 5G |
€373.00
|
1 | 6 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | S0230 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__4N__2O__7 = 380.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 6106-46-3 |
| Related CAS RN
|
13265-10-6 |
| Reaxys Registry Number | 11258389 |
| PubChem Substance ID | 87575767 |
| Merck Index (14) | 8406 |
| MDL Number | MFCD00078239 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 195.0 to 199.0 °C |
| Specific rotation [a]20/D | -23.0 to -27.0 deg(C=1, H2O) |
| Solubility in Water | almost transparency |
Properties (reference)
| Melting Point | 199 °C |
| Specific Rotation | -25° (C=1,H2O) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H310 + H330 : Fatal in contact with skin or if inhaled. H302 : Harmful if swallowed. |
| Precautionary Statements | P260 : Do not breathe dust. P262 : Do not get in eyes, on skin, or on clothing. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing. P302 + P352 + P310 : IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. |
Related Laws:
| EC Number | 228-065-2 |
| RTECS# | YM3675150 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Scopolamine Methyl Nitrate: A Belladonna Alkaloid with Anticholinergic Activity
Scopolamine salts ([S0021][ S0230] and [S0231]), belladonna alkaloids, are anticholinergic agents. Their free base, scopolamine competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine [A0754] as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al. (The product is for research purpose only.)
References
- Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response
- Effects of cholinergic and monoaminergic antagonists and tranquilizers upon spatial memory in rats
- Scanning mutagenesis studies of the M1 muscarinic acetylcholine receptor
- High-pressure liquid chromatographic determination of methscopolamine nitrate, phenylpropanolamine hydrochloride, pyrilamine maleate, and pheniramine maleate in tablets
- Determination of phenylephrine hydrochloride, chlorpheniramine maleate, and methscopolamine nitrate in tablets or capsules by liquid chromatography with two UV absorbance detectors in series
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