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CAS RN: 51-55-8 | Product Number: A0754

Atropine


Purity: >99.0%(T)
Synonyms:
  • (±)-Hyoscyamine
Documents:
5G
A$324.00
≥20  ≥20 
25G
A$1,089.00
2   3  
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Product Number A0754
Purity / Analysis Method >99.0%(T)
Molecular Formula / Molecular Weight C__1__7H__2__3NO__3 = 289.38  
Physical State (20 deg.C) Solid
Store Under Inert Gas Store under inert gas
Condition to Avoid Light Sensitive,Air Sensitive
CAS RN 51-55-8
Reaxys Registry Number 91256
PubChem Substance ID 87562295
SDBS (AIST Spectral DB) 7817
Merck Index (14) 875
MDL Number

MFCD00022622

Specifications
Appearance White powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 99.0 %
Melting point 114.0 to 118.0 °C
Solubility in Methanol almost transparency
Properties (reference)
Melting Point 116 °C
Solubility in water Practically insoluble
Degree of solubility in water 2.2 g/l   25 °C
Solubility (very soluble in) Ethanol,Chloroform
Solubility (soluble in) Methanol,Benzene
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 + H331 : Toxic if swallowed or if inhaled.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P304 + P340 + P311 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
Related Laws:
RTECS# CK0700000
Transport Information:
UN Number UN1544
Class 6.1
Packing Group III
H.S.code* 2939.79-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Atropine: A Nonselective Muscarinic Acetylcholinergic Receptors Antagonist

Atropine, a tropane alkaloid, is a free base of its sulfate [A0550] which was first extracted from the root of belladonna (Atropa belladonna) in 1830s. Atropine is a enantiomeric mixture of (R,S)-hyoscyamine (dl-hyoscyamine), racemization occurring during the extraction procedure, whereas only (S)-hyoscyamine (l-hyoscyamine) [H0450] is the active isomer. Atropine is a competitive antagonist of muscarine-like actions of acetylcholine and is therefore classified as an antimuscarinic agent. Atropine does not distinguish among the M1, M2, and M3 subgroups of muscarinic receptors. Atropine inhibits the action of acetylcholine at postganglionic nerve endings, thus affecting receptors of the exocrine glands, smooth muscle, cardiac muscle and the central nervous system. (The product is for research purpose only.)

References


PubMed Literature


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