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CAS RN: 849217-48-7 | Product Number: F1083
1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid
![Chemical Structure of 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid](/medias/F1083.jpg?context=bWFzdGVyfHJvb3R8NDI1Mjh8aW1hZ2UvanBlZ3xhR05rTDJoaU5DODRPVEl4T0RJNE1EazRNRGM0TDBZeE1EZ3pMbXB3Wnd8MGY1MTViZDUyMTJmYzA2MWM1ZWExZTU2Y2IwMWEzZTE0MmZhY2QxNGIzMjA4NThlZTU4N2Q0ODdlMjE0ZTg4NQ "1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid")
![Thumbnail of 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid](/medias/F1083.jpg?context=bWFzdGVyfHJvb3R8MTQyODJ8aW1hZ2UvanBlZ3xhRE16TDJneVpTODRPVE0xTWpFNU1qWTFOVFkyTDBZeE1EZ3pMbXB3Wnd8ZmQ2NDc0NzE3MTczZWY0ZGZkMDFjNWVhYzkyMDM1YjQwYWYwN2U3OWM0YTljNjBiNzFmNjVkZjdiMzFjNzVmOQ)
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![1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid")
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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| 1G |
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| Product Number | F1083 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__0FNO__3 = 223.20 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 849217-48-7 |
| Reaxys Registry Number | 15712708 |
| PubChem Substance ID | 354334439 |
| MDL Number | MFCD11226313 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 173.0 to 177.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 175 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2924.29-000 |
Application
A Synthetic Intermediate of c-Met and Other Tyrosine Kinases
This product is used for the synthesis of inhibitors of c-Met and other tyrosine kinases
References
- Bioorthogonal small molecule imaging agents allow single-cell imaging of MET
- Discovery of Anilinopyrimidines as Dual Inhibitors of c-Met and VEGFR-2: Synthesis, SAR, and Cellular Activity
PubMed Literature
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