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CAS RN: 1847-24-1 | Product Number: F1372
Flucloxacillin Sodium
Purity: >95.0%(HPLC)
Synonyms:
- Floxacillin Sodium
- Sodium (2R,5R,6S)-6-[3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
Product Documents:
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| Product Number | F1372 |
Purity / Analysis Method
|
>95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__9H__1__6ClFN__3NaO__5S = 475.85 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1847-24-1 |
| Reaxys Registry Number | 5402507 |
| MDL Number | MFCD01682108 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Specific rotation | +150 to +170 deg(C=1, water) |
| Water | max. 4.5 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 180 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | XH8680000 |
Transport Information:
| H.S.code* | 2941.10-000 |
Application
Flucloxacillin Sodium: An Antimicrobial Resistant Against Penicillinase
Flucloxacillin sodium is a synthetic penicillin used to treat infections caused by Staphylococcus aureus. It is an antimicrobial resistant against penicillinase, an enzyme responsible for cleaving the beta-lactam ring of penicilins. (The product is for research use only.)
References
- Bactericidal activity of flucloxacillin against Staphylococcus aureus in primary keratinocyte cultures of lesional and unaffected skin of patients suffering from atopic dermatitis
- Development and validation of RP-HPLC method for simultaneous estimation of amoxicillin trihydrate and flucloxacillin flucloxacillin sodium in capsule dosage form
- Flucloxacillin : A Review of Characteristics, Properties and Analytical Methods
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