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CAS RN: 1405-86-3 | Product Number: G0150
Glycyrrhizin
Purity: >75.0%(HPLC)
Synonyms:
- Glycyrrhizic Acid
Product Documents:
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| Product Number | G0150 |
Purity / Analysis Method
|
>75.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__4__2H__6__2O__1__6 = 822.94 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1405-86-3 |
| Reaxys Registry Number | 77922 |
| PubChem Substance ID | 87570348 |
| SDBS (AIST Spectral DB) | 4953 |
| Merck Index (14) | 4505 |
| MDL Number | MFCD00065194 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 75.0 area% |
| Purity(Neutralization titration) | min. 93.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +56.0 to +63.0 deg(C=1.5, EtOH)(calcd.on anh.substance) |
| Water | max. 7.0 % |
Properties (reference)
| Specific Rotation | 61° (C=1.5,EtOH) |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | MD2025000 |
Transport Information:
| H.S.code* | 2938.90-000 |
Application
Glycyrrhizin: The Major Triterpenoid Saponin of Licorice Root
Glycyrrhizin (or glycyrrhizin acid) is the major triterpenoid saponin of licorice root (Glycyrrhiza glabra)1,2) which have long been widely used as a natural sweetener (an agonist of the human sweet taste receptor)3) and a herbal medicine. It has been reported that glycyrrhizin possess a wide range of pharmacological properties, such as anti-inflammatory, anti-ulcer, anti-allergic, anti-dote, anti-oxidant, anti-tumor, anti-viral etc.4-6) (The product is for research purpose only.)
References
- 1) Simultaneous HPLC analysis, with isocratic elution, of glycyrrhizin and glycyrrhetic acid in liquorice roots and confectionery products
- 2) The determination of glycyrrhizic acid in Glycyrrhiza uralensis Fisch. ex DC. (ZhiGanCao) root and the dried aqueous extract by LC-DAD
- 3) Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells
- 4) Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin (a review)
- 5) Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds
- 6) Antiviral effects of Glycyrrhiza species (a review)
PubMed Literature
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