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CAS RN: 126-07-8 | Product Number: G0384
(+)-Griseofulvin
Purity: >95.0%(HPLC)(qNMR)
Synonyms:
Product Documents:
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| Product Number | G0384 |
Purity / Analysis Method
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__1__7H__1__7ClO__6 = 352.77 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 126-07-8 |
| Reaxys Registry Number | 95226 |
| PubChem Substance ID | 135727206 |
| Merck Index (14) | 4549 |
| MDL Number | MFCD00082343 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| Melting point | 218.0 to 222.0 °C |
| Specific rotation [a]20/D | +355.0 to +370.0 deg(C=1, DMF) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 220 °C |
| Specific Rotation | 360° (C=1,DMF) |
| Maximum Absorption Wavelength | 321 nm (CHCl__3) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Dimethylformamide |
| Solubility (slightly sol. in) | Chloroform, Ethanol, Acetone, Methanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H371 : May cause damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. H340 : May cause genetic defects. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
| RTECS# | WG9800000 |
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Studies on Antifungal Activity
Reference
- Synthesis, antimicrobial and antifungal activity of a new class of spiro pyrrolidines
Application
Preparation of Griseofulvin Nanoparticles
References
- Production of antibiotic micro- and nano-particles by supercritical antisolvent precipitation
- Production of griseofulvin nanoparticles using supercritical CO2 antisolvent with enhanced mass transfer
- Preparation of griseofulvin nanoparticles from water-dilutable microemulsions
- Preparation and dissolution characteristics of several fast-release solid dispersions of griseofulvin
PubMed Literature
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Specifications
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