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CAS RN: 32316-92-0 | Product Number: N0649
2-Naphthaleneboronic Acid (contains varying amounts of Anhydride)
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Purity:
Synonyms:
- 2-Naphthylboronic Acid (contains varying amounts of Anhydride)
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
A$50.00
|
0 | 10 | Contact Us | |
| 5G |
A$127.00
|
≥40 | 5 | Contact Us | |
| 25G |
A$428.00
|
3 | ≥100 | Contact Us |
* Please contact our distributor of Chem-Supply
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email: sales@chemsupply.com.au)
* ChemSupply Australia Pty Ltd (Phone: 08-8440-2000 / email: sales@chemsupply.com.au)
| Product Number | N0649 |
| Molecular Formula / Molecular Weight | C__1__0H__9BO__2 = 171.99 |
| Physical State (20 deg.C) | Solid |
Storage Temperature 
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 32316-92-0 |
| Reaxys Registry Number | 2936449 |
| PubChem Substance ID | 87573961 |
| MDL Number | MFCD00236051 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(Neutralization titration) | 97.0 to 112.0 % |
Properties (reference)
| Melting Point | 268 °C |
| Solubility in water | Slightly soluble |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2931.90-000 |
Application
Efflux pump research
2-Naphthaleneboronic acid has been reported to act as an inhibitor of Staphylococcus aureus NorA efflux pump.1) The compound was found to potentiate ciprofloxacin activity by a 4-fold increase at concentrations ranging at 4-8 μg/ml against S. aureus 1199B, which overexpresses NorA.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) First Identification of Boronic Species as Novel Potential Inhibitors of the Staphylococcus aureus NorA Efflux Pump
- β-Lactamases and β-Lactamase Inhibitors in the 21st Century
- Structure-Based Enhancement of Boronic Acid-Based Inhibitors of AmpC β-Lactamase
Application
AmpC β-lactamase inhibitor
The primary resistance mechanism of microbes to β-lactam antibiotics is hydrolysis of the antibiotics by β-lactamase.1) 2-Naphthaleneboronic acid is one of boronic acid compounds having β-lactamase (AmpC) inhibition activity (Ki = 8.5 ± 1.8 μM).2)
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