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CAS RN: 59-67-6 | Product Number: N1103
Nicotinic Acid [Matrix for MALDI-TOF/MS]
![Chemical Structure of Nicotinic Acid [Matrix for MALDI-TOF/MS]](/medias/N1103.jpg?context=bWFzdGVyfHJvb3R8NDY0MTV8aW1hZ2UvanBlZ3xhRGszTDJnMU5DODRPVEl5TnpVME56YzNNVEU0TDA0eE1UQXpMbXB3Wnd8ZWE0NGQxYzZiN2MxOTI4MDlmM2IzYjgxYjEyNWM5MjExZGU2OTRjM2NjZDFkMDNlNzhkOTM3YzEzN2IxZjYyOQ "Nicotinic Acid [Matrix for MALDI-TOF/MS]")
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Purity: >99.5%(T)(HPLC)
Synonyms:
- Niacin
- Pyridine-3-carboxylic Acid
- Vitamin B3
Product Documents:
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| Product Number | N1103 |
Purity / Analysis Method 
|
>99.5%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__6H__5NO__2 = 123.11 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 59-67-6 |
| Reaxys Registry Number | 109591 |
| PubChem Substance ID | 354334656 |
| SDBS (AIST Spectral DB) | 7944 |
| Merck Index (14) | 6525 |
| MDL Number | MFCD00006391 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 99.5 area% |
| Purity(Neutralization titration) | min. 99.5 % |
| Melting point | 236.0 to 240.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 238 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | QT0525000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
MALDI-TOF質量分析法におけるマトリックス
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is a standard soft ionization technique in mass spectrometry. Nicotinic acid is often used as a matrix for MALDI-TOF mass spectrometry, for peptide/protein analysis in particular. Incidentally, IUPAC defined standard terms relating to mass spectrometry in 2013 (free access).
References
- Influence of the wavelength in high-irradiance ultraviolet laser desorption mass spectrometry of organic molecules
- Matrix-assisted ultraviolet laser desorption of non-volatile compounds
- Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons
- Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)
PubMed Literature
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Other Documents
Related Products
Nicotinic Acid
| Product # | N0082 |
| CAS RN | 59-67-6 |
| Purity / Analysis Method: | >99.0%(T)(HPLC) |