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CAS RN: 26864-56-2 | Product Number: P2076
Penfluridol
Purity: >98.0%(T)
Synonyms:
- 1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol
Product Documents:
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| Product Number | P2076 |
Purity / Analysis Method
|
>98.0%(T) |
| Molecular Formula / Molecular Weight | C__2__8H__2__7ClF__5NO = 523.97 |
| Physical State (20 deg.C) | Solid |
Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 26864-56-2 |
| Reaxys Registry Number | 1558826 |
| PubChem Substance ID | 253660023 |
| Merck Index (14) | 7087 |
| MDL Number | MFCD00866714 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 106.0 to 110.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 108 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | TN6957000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2933.39-000 |
Application
Studies of the Antipsychotic Properties of a Diphenylbutylpiperdine Derivative, Penfluridol
References
- Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists
- Preferential block of T-type calcium channels by neuroleptics in neural crest-derived rat and human C cell lines
- J. J. Enyeart, B. A. Biagi, B. Mlinar, Mol. Pharmacol. 1992, 42, 364.
- Maitotoxin-elicited calcium influx in cultured cells. Effect of calcium-channel blockers
- β-Subunit coexpression and the α1 subunit domain I-II linker affect piperidine block of neuronal calcium channels
- G. W. Zamponi, T. W. Soong, E. Bourinet, T. P. Snutch, J. Neurosci. 1996, 16, 2430.
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