text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 105826-92-4 | Product Number: T2743

Tropisetron Hydrochloride


Purity: >98.0%(T)(HPLC)
Synonyms:
  • (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-Indole-3-carboxylate Hydrochloride
Documents:
1G
A$354.00
2   1  
5G
A$1,225.00
19   10  
* Please contact our distributor of Chem-Supply if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination.
* Chem-Supply Pty Ltd (Phone: 08-8440-2000 / email:  info@chemsupply.com.au)

Product Number T2743
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__2__0N__2O__2·HCl = 320.82  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 105826-92-4
Related CAS RN 89565-68-4
Reaxys Registry Number 8883131
PubChem Substance ID 160871173
Merck Index (14) 9783
MDL Number

MFCD00210221

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 285 °C(dec.)
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Danger
Hazard Statements H301 : Toxic if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P405 : Store locked up.
Related Laws:
RTECS# NL6012520
Transport Information:
UN Number UN2811
Class 6.1
Packing Group III
Application
Tropisetron hydrochloride: A Selective Competitive 5-HT3 Receptor Antagonist

Tropisetron hydrochloride is a selective competitive antagonist of 5-hydroxytryptamine 3 (5-HT3) receptor which is a subclass of serotonin receptors. 5-HT3 receptors are located peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, known as the emetic center of the brain. Therefore, tropisetron is used for the prevention of chemotherapy-induced nausea and vomiting.1,2) Tropisetron is mainly metabolized by cytochrome P450 (CYP) 2D6.3) In 2000’s, it has been reported that tropisetron is also a selective partial agonist at α7 nicotinic acetylcholine receptors (α7nAChRs). 4,5) (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Documents
Safety Data Sheet (SDS) Search
Please select Language.

The requested SDS is not available.

• Please check that the Product Number you have entered is correct.

• If your information is correct and you are still not able to view the requested SDS,  please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Other Documents