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CAS RN: 313-67-7 | Product Number: A3599
Aristolochic Acid
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Purity: >95.0%(T)(HPLC)
Synonyms:
- TR 1736
- 8-Methoxy-6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic Acid
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
€299.00
|
Contact Us | 7 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | A3599 |
Purity / Analysis Method 
|
>95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__1NO__7 = 341.28 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 313-67-7 |
| Reaxys Registry Number | 345159 |
| MDL Number | MFCD00004996 |
Specifications
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 278 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H350 : May cause cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 206-238-3 |
| RTECS# | CF3325000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2939799090 |
Application
Aristolochic Acid: A Carcinogenic, Mutagenic, and Nephrotoxic Phytochemical
Aristolochic acid is a carcinogenic, mutagenic, and nephrotoxic phytochemical found in the flowering plant family Aristolochiaceae, which has been widely used as a traditional herbal medicine to treat kidney and urinary problems. In 1994, Vanherweghem et al. reported that a cause of progressive interstitial fibrosis of the kidney was associated with herbs containing aristolochic acid.1) Since then, aristolochic acid has been reported to be associated with the development of progressive interstitial fibrosis of the kidney, called aristolochic acid nephropathy (AAN), and with urothelial cancer in AAN patients.2-4) (The product is for research purpose only.)
References
- 1) Identification of aristolochic acid in Chinese herbs
- 2) Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)
- 3) Aristolochic acid and the etiology of endemic (Balkan) nephropathy
- 4) An integrated view of aristolochic acid nephropathy: update of the literature (a review)
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