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CAS RN: 202189-78-4 | Product Number: B5392

Bilastine

Chemical Structure of Bilastine
×
× Bilastine

Purity: >98.0%(T)(HPLC)
Synonyms:
  • 2-[4-[2-[4-[1-(2-Ethoxyethyl)-1H-benzo[d]imidazol-2-yl]piperidin-1-yl]ethyl]phenyl]-2-methylpropanoic Acid
Product Documents:
SDS | Specifications | C of A & Other Certificates | Analytical Charts

General Information | Specifications & Properties | Safety & Regulations | Applications & Literature

Explanatory notes for this page

250MG
€254.00
 1   ≥60 
1G
€685.00
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Product Number B5392
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__8H__3__7N__3O__3 = 463.62 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
Packaging and Container 250MG-Glass Bottle with Plastic Insert (View image)
CAS RN 202189-78-4
Reaxys Registry Number 13851185
PubChem Substance ID 354335500
MDL Number

MFCD09837814
Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 199.0 to 203.0 °C
Properties (reference)
Melting Point 202 °C
Solubility in water Insoluble
Solubility (insoluble in) Methanol
GHS
Related Laws:
Transport Information:
HS Number 2933998090
Application
Bilastine: A Selective Histamine H1 Receptor Antagonist

Bilastine is a selective histamine H1 receptor antagonist. On the other hand, the results of studies on bilastine confirmed the lack of significant antagonism against not only histamine H2 and H3 receptors but also serotonin, bradykinin, leukotriene D4, calcium, muscarinic M3-receptors, α1-adrenoceptors, and β2-adrenoceptors. Furthermore, bilastine do not cause sedation or interact with cytochrome P 450. Therefore, bilastine is used as a second generation H1-antihistamine for the treatment of allergic rhinitis and chronic urticarial. For your reference, [P2382] is a synthetic intermediate of bilastine.(The product is for research purpose only.)

References


PubMed Literature


Documents

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