text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 530-62-1 | Product Number: C0119

1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis]

Purity: >97.0%(T)
  • 1,1'-Carbonylbis-1H-imidazole
  • CDI
2   ≥20 
13   ≥20 
Contact Us ≥20 

*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).

Product Number C0119
Purity / Analysis Method >97.0%(T)
Molecular Formula / Molecular Weight C__7H__6N__4O = 162.15  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Moisture Sensitive,Heat Sensitive
CAS RN 530-62-1
Reaxys Registry Number 6826
PubChem Substance ID 87565300
SDBS (AIST Spectral DB) 21181
Merck Index (14) 1819
MDL Number


Appearance White to Light yellow powder to crystal
Purity(Neutralization titration) min. 97.0 %
Melting point 114.0 to 121.0 °C
Properties (reference)
Melting Point 118 °C
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H314 : Causes severe skin burns and eye damage.
Precautionary Statements P260 : Do not breathe dust or mist.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
Related Laws:
EC Number 208-488-9
Transport Information:
UN Number UN1759
Class 8
Packing Group III
HS Number 2933299090
Condensation of Amino Acides Using 1,1’- Carbonyldiimidazole

Typical Procedure:
To a solution of N-Cbz-glycine (2.09 g, 0.010 mol) in dry THF (10 mL) is added 1,1’-carbonyldiimidazole (CDI) (1.62 g, 0.010 mol). After stirring for 1.5 hour, L-tyrosine ethyl ester (2.09 g, 0.010 mol) is added to the solution and the reaction mixture is stirred overnight. Then THF is removed by an evaporator and 1 N-HCl (50 mL) is added. Cooling of the solution gives a solid. This is washed with water and 5% NaHCO3. The solid is filtered and washed with water again. After drying, the product is recrystallized from 50% ethanol to give ethyl N-Cbz-glycine- L -tyrosine ethyl ester (3.79 g, yield 95%).


PubMed Literature

Safety Data Sheet (SDS) Search
Please select Language.

The requested SDS is not available.

• Please check that the Product Number you have entered is correct.

• If your information is correct and you are still not able to view the requested SDS,  please Contact Us for more information.

C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number is entered
Other Documents