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CAS RN: 64-86-8 | Product Number: C0380

Colchicine (contains 5% Ethyl Acetate at maximum)


Purity: >97.0%(HPLC)
Synonyms:
Documents:
500MG
€44.00
4   ≥20 
5G
€208.00
10   ≥20 

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Product Number C0380
Purity / Analysis Method >97.0%(HPLC)
Molecular Formula / Molecular Weight C__2__2H__2__5NO__6 = 399.44  
Physical State (20 deg.C) Solid
Condition to Avoid Light Sensitive,Hygroscopic
CAS RN 64-86-8
Reaxys Registry Number 2228813
PubChem Substance ID 87565511
Merck Index (14) 2471
MDL Number

MFCD00078484

Specifications
Appearance White to Orange to Green powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Nonaqueous Titration) min. 95.0 %(calcd.on dried substance)
Specific rotation [a]20/D -230 to -245 deg(C=1, EtOH)
Drying loss max. 5.0 %
Properties (reference)
Melting Point 150 °C
Specific Rotation -238° (C=1,EtOH)
Solubility in water Soluble
Solubility (very soluble in) Chloroform,Alcohol
Solubility (soluble in) Methanol
Solubility (very slightly) Benzene,Ether
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 : Fatal if swallowed.
H340 : May cause genetic defects.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 200-598-5
RTECS# GH0700000
Transport Information:
UN Number UN1544
Class 6.1
Packing Group III
HS Number 2939790090
Application
Colchicine: An Antimitotic Alkaloid

Colchicine is an alkaloid, extracted from plants of the genus Colchicum. Colchicine inhibits β-tubulin polymerization into microtubules by binding to tubulin. Thus, colchicine is an antimitotic agent with a great pharmaceutical potential as an antitumor agent. Colchicine also inhibits neutrophil motility and activity, leading to a net anti-inflammatory effect. (The product is for research purpose only.)

References


PubMed Literature


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