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CAS RN: 41100-52-1 | Product Number: D3608

3,5-Dimethyl-1-adamantanamine Hydrochloride


Purity: >98.0%(T)(N)
Synonyms:
  • 1-Amino-3,5-dimethyladamantane Hydrochloride
  • Memantine Hydrochloride
Documents:
5G
€78.00
7   ≥20 
25G
€271.00
2   6  

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Product Number D3608
Purity / Analysis Method >98.0%(T)(N)
Molecular Formula / Molecular Weight C__1__2H__2__1N·HCl = 215.77  
Physical State (20 deg.C) Solid
CAS RN 41100-52-1
Related CAS RN 19982-08-2
Reaxys Registry Number 7937891
PubChem Substance ID 87559918
Merck Index (14) 5806
MDL Number

MFCD00214336

Specifications
Appearance White to Almost white powder to crystal
Purity(with Total Nitrogen) min. 98.0 %
Purity(Argentmetric Titration) min. 98.0 %
Properties (reference)
Melting Point 292 °C
Solubility in water Soluble
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
EC Number 255-219-6
Transport Information:
HS Number 2921309990
Application
Memantine Hydrochloride: A Moderate-Affinity and Uncompetitive N-Methyl-D-Aspartate (NMDA) Receptor Antagonist

Memantine hydrochloride is a moderate-affinity and uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. NMDA receptor (NMDAR) is a subtype of glutamate receptor, and very important for controlling synaptic plasticity and memory function. Persistent activation of central nervous system NMDAR by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease. Memantine binds preferentially in moderate to the NMDAR-operated cation channels, blocks current flow through the NMDARs, and controls the activity of the NMDARs. Therefore, memantine is used for the treatment of Alzheimer’s disease. (The product is for research purpose only.)

References


PubMed Literature


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