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CAS RN: 2590-41-2 | Product Number: D5471
6-Dehydronandrolone Acetate
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Purity: >98.0%(HPLC)
Synonyms:
- 17β-Acetoxyestra-4,6-dien-3-one
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€ 46,00
|
Ships within 3 weeks after ordering | 12 |
|
|
| 5G |
€ 148,00
|
2 | 1 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | D5471 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__6O__3 = 314.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 2590-41-2 |
| Reaxys Registry Number | 3121674 |
| MDL Number | MFCD00271529 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 106.0 to 110.0 °C |
| Specific rotation [a]20/D | -37.0 to -40.0 deg(C=1,CHCl3) |
Properties (reference)
| Melting Point | 108 °C |
| Specific Rotation | -38° (C=1,CHCl3) |
| Maximum Absorption Wavelength | 283 nm (MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
Transport Information:
| HS Number | 2915390090 |
Application
A Key Synthetic Intermediate for the Synthesis of 7-Alkylated Steroids
6-Dehydronandrolone acetate is a key synthetic intermediate for the synthesis of 7-alkylated steroids, such as tibolone [T2330] and fulvestrant [F1144].
References
- Fulvestrant: From the Laboratory to Commercial-Scale Manufacture
- Development of a Catalytic Cuprate 1,6-Conjugate Dienone Addition Process for the Manufacture of Fulvestrant EAS, a Key Intermediate in the Synthesis of Fulvestrant
- An alternative synthesis of the breast cancer drug fulvestrant (Faslodex): catalyst control over C-C bond formation
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