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CAS RN: 56296-78-7 | Product Number: F0750

Fluoxetine Hydrochloride

Purity: >98.0%(T)(HPLC)
  • N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride
9   ≥20 
8   ≥20 

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Product Number F0750
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__8F__3NO·HCl = 345.79  
Physical State (20 deg.C) Solid
CAS RN 56296-78-7
Related CAS RN 54910-89-3
Reaxys Registry Number 6759273
PubChem Substance ID 125307843
SDBS (AIST Spectral DB) 52894
MDL Number


Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 157.0 to 161.0 °C
Properties (reference)
Melting Point 159 °C
Solubility in water Soluble
Pictogram Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H318 : Causes serious eye damage.
H400 : Very toxic to aquatic life.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P264 : Wash skin thoroughly after handling.
P280 : Wear eye protection/ face protection.
P391 : Collect spillage.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
Related Laws: / Compliance with laws, Regulations
Enzyme Commission 260-101-2
RTECS# UI4050000
Transport Information:
UN Number UN3077
Class 9
Packing Group III
HS Number 2922190090
Fluoxetine Hydrochloride: A Selective Serotonin Reuptake Inhibitor (SSRI) with a Long-Half Life

Fluoxetine hydrochloride is a selective serotonin reuptake inhibitor (SSRI). SSRIs do not blockade of acetylcholine or norepinephrine receptors. Therefore, blockade of reuptake is confined to serotonin (5-HT) [S0370] of central nervous system neurons. Although the exact mechanism is unknown, SSRIs are a widely used type of antidepressant medication. Fluoxetine has a long duration of action since the N-demethylated metabolite (norfluoxetine [CAS: 83891-03-6]) is also active.
In general, SSRIs possess a protonatable nitrogen atom and simple aromatic moisture, instead of a larger aromatic ring system. Besides fluoxetine, SSRIs includes citalopram hydrobromide [C2370], (S)-citalopram oxalate [E0958], sertraline hydrochloride [S0507] paroxetine hydrochloride [P1977] and a few other agents. (The product is for research purpose only.)


PubMed Literature

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