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CAS RN: 146-56-5 | Product Number: F1240
Fluphenazine Dihydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- 2-[4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
€ 103,00
|
3 | 5 |
|
|
| 5G |
€ 344,00
|
1 | 5 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | F1240 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__2H__2__6F__3N__3OS·2HCl = 510.44 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 146-56-5 |
| Reaxys Registry Number | 3830953 |
| PubChem Substance ID | 468591872 |
| Merck Index (14) | 4189 |
| MDL Number | MFCD00055212 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 225.0 to 231.0 °C |
Properties (reference)
| Melting Point | 227 °C |
| Maximum Absorption Wavelength | 311 nm (MeOH) |
| Solubility in water | Soluble |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H360 : May damage fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. |
Related Laws:
| EC Number | 205-674-1 |
| RTECS# | TL9800000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2934309090 |
Application
Fluphenazine Dihydrochloride: A Typical Antipsychotic Agent
Fluphenazine dihydrochloride is a typical antipsychotic agent. Fluphenazine exerts activity at various levels of the central nervous system as well as on peripheral organ systems. Reportedly, fluphenazine acts as a dopamine D1 and D2 receptors antagonist.1,2) It also acts as a histamine H1 and serotonin 5-HT2A receptors inverse agonist.3) (The product is for research purpose only.)
References
- Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
- Dopamine D1A receptor function in a rodent model of tardive dyskinesia
- 5-Hydroxytryptamine2A Receptor Inverse Agonists as Antipsychotics
- Fluphenazine hydrochloride (a review on the physical properties like pka, pH, melting range, solubility analysis, and crystalline properties)
- Simultaneous determination of nortriptyline hydrochloride and fluphenazine hydrochloride in microgram quantities from low dosage forms by liquid chromatography-uv detection
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