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Published TCIMAIL newest issue No.198
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CAS RN: 6054-98-4 | Product Number: O0517
Olsalazine Sodium
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Purity: >98.0%(HPLC)
Synonyms:
- 5,5'-Azobis(2-hydroxybenzoic Acid Sodium Salt)
- 4,4'-Dihydroxyazobenzene-3,3'-dicarboxylic Acid Disodium Salt
- Mordant Yellow 5
- Disodium 5,5'-(Diazene-1,2-diyl)bis(2-hydroxybenzoate)
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 250MG |
€26.00
|
1 | 15 |
|
| 1G |
€78.00
|
Contact Us | 32 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0517 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__8N__2Na__2O__6 = 346.21 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 6054-98-4 |
| Related CAS RN
|
15722-48-2 |
| Reaxys Registry Number | 9027885 |
| PubChem Substance ID | 354335800 |
| Merck Index (14) | 6841 |
| MDL Number | MFCD00013300 |
Specifications
| Appearance | Light yellow to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
Properties (reference)
| Melting Point | 294 °C(dec.) |
| Solubility in water | Soluble |
| Solubility (insoluble in) | Ether, Chloroform, Ethanol |
GHS
Related Laws:
| EC Number | 227-975-7 |
Transport Information:
| HS Number | 2927000090 |
Application
Olsalazine Sodium: A Prodrug of 5-Aminosalicylic Acid (5-ASA)
Olsalazine sodium is a prodrug of 5-aminosalicylic acid (5-ASA) [A0317] which is an anti-inflammatory agent. Olsalazine is formed by combining two 5-ASA molecules with an azo bond, and is split by intestinal bacteria to two 5-ASA. Olsalazine sodium is commonly used in the treatment of inflammatory bowel diseases (IBD) such as ulcerative colitis and Crohn's disease (CD) and rheumatoid arthritis (RA). (The product is for research purpose only.)
References
- Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease
- Azo chemistry and its potential for colonic delivery (a review)
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
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