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CAS RN: 191217-81-9 | Product Number: P2073

Pramipexole Dihydrochloride Monohydrate


Purity: >98.0%(HPLC)(N)
Synonyms:
  • (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole Dihydrochloride Monohydrate
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100MG
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Product Number P2073
Purity / Analysis Method >98.0%(HPLC)(N)
Molecular Formula / Molecular Weight C__1__0H__1__7N__3S·2HCl·H__2O = 302.26  
Physical State (20 deg.C) Solid
CAS RN 191217-81-9
Related CAS RN 104632-25-9&104632-26-0
Reaxys Registry Number 14116907
PubChem Substance ID 253659970
Merck Index (14) 7705
MDL Number

MFCD02183927

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %
Specific rotation [a]20/D -65.0 to -71.0 deg(C=1,MeOH)
Water 5.0 to 7.0 %
Properties (reference)
Melting Point 290 °C(dec.)
Specific Rotation -67° (C=1,MeOH)
Solubility in water Soluble
Solubility (soluble in) Methanol
Solubility (very slightly) Ethanol
Solubility (insoluble in) dichloromethane
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
H336 : May cause drowsiness or dizziness.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P261 : Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
Related Laws: / Compliance with laws, Regulations
RTECS# DL3375000
Transport Information:
HS Number 2934208090
Application
A Dopamine D3 and D2 Receptor Agonist, Pramipexole

Pramipexole dihydrochloride, which is a dopamine agonist, has selective affinity for dopamine receptors of the D2 subfamily (D2, D3, D4), with a 7-10 fold greater affinity for D3 than for D2 receptor subtypes; affinity for the D4 receptor subtype is 17-fold less than for D3 receptors. For your reference, [D4337] is a key synthetic building block of pramipexole dihydrochloride.

References


PubMed Literature


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