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CAS RN: 179474-81-8 | Product Number: P2467
Prucalopride
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Purity: >98.0%(HPLC)
Synonyms:
- 4-Amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydrobenzofuran-7-carboxamide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
€ 32,00
|
1 | 10 |
|
|
| 50MG |
€ 112,00
|
Contact Us | 18 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | P2467 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__6ClN__3O__3 = 367.87 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 179474-81-8 |
| Reaxys Registry Number | 8357099 |
| PubChem Substance ID | 468592610 |
| MDL Number | MFCD09837787 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Water | max. 7.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 92 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | DF6472550 |
Transport Information:
| HS Number | 2934999090 |
Application
Prucalopride: A Selective Serotonin Type 4 (5-HT4) Receptor Agonist
Prucalopride, a dihydrobenzofuran-carboxamide derivative, is a selective serotonin type 4 (5-HT4) receptor agonist that stimulates colonic peristalsis, which increases bowel motility. It has been reported that prucalopride is devoid of effects mediated via other receptors in vitro (such as 5-HT1B, 5-HT1D, and 5-HT2B) that leading to adverse cardiovascular events. (The product is for research purpose only.)
References
- The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound
- Role of prucalopride, a serotonin (5-HT4) receptor agonist, for the treatment of chronic constipation (a review)
- 5-HT4 receptor agonists: similar but not the same (a review)
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