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CAS RN: 111974-72-2 | Product Number: Q0092

Quetiapine Hemifumarate


Purity: >98.0%(T)(HPLC)
Synonyms:
Documents:
5G
€70.00
3   8  
25G
€245.00
2   4  

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Product Number Q0092
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__1H__2__5N__3O__2S·^^1/__2C__4H__4O__4 = 441.55  
Physical State (20 deg.C) Solid
CAS RN 111974-72-2
Related CAS RN 111974-69-7
Reaxys Registry Number 8378094
PubChem Substance ID 160871365
Merck Index (14) 8039
MDL Number

MFCD03423782

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Purity(Neutralization titration) min. 98.0 %
Melting point 172.0 to 176.0 °C
Properties (reference)
Melting Point 174 °C
Solubility in water Practically insoluble
Solubility (soluble in) Dimethylformamide
Solubility (slightly sol. in) Methanol
Solubility (very slightly) Ethanol
Solubility (insoluble in) Ether
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H370 : Causes damage to organs.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws: / Compliance with laws, Regulations
RTECS# KK3605000
Transport Information:
HS Number 2934999090
Application
Quetiapine Hemifumarate: A Multi-Acting Receptor Targeted Antipsychotic (MARTA)

Quetiapine hemifumarate is known as a multi-acting receptor targeted antipsychotic (MARTA), such as clozapine [C2547] and olanzapine [O0393]. Quetiapine has greater affinity for serotonin 5-HT2A and dopamine D1 and D2 receptors. Furthemore, quetiapine has various affinities for multiple receptors, including 5-HT1A and α1- and α2-adrenergic receptors. While, quetiapine binds weakly to benzodiazepine (BZD) and muscarinergic M1A receptors. The precise mechanism of action is unknown, but quetiapine is used as a thienobenzodiazepine atypical antipsychotic. (The product is for research purpose only.)

References


PubMed Literature


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