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Published TCIMAIL newest issue No.198
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CAS RN: 25913-34-2 | Product Number: T3630
Tinoridine Hydrochloride
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Purity: >98.0%(HPLC)
Synonyms:
- Ethyl 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate Hydrochloride
- 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic Acid Ethyl Ester Hydrochloride
- 2-Amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€178.00
|
Contact Us | 2 |
|
| 100MG |
€429.00
|
Contact Us | 12 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | T3630 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__0N__2O__2S·HCl = 352.88 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic |
| CAS RN | 25913-34-2 |
| Reaxys Registry Number | 13518040 |
| PubChem Substance ID | 468592876 |
| MDL Number | MFCD01680536 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 7.50 to 8.50 % |
| NMR | confirm to structure |
Properties (reference)
GHS
| Pictogram |
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| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 247-342-9 |
| RTECS# | XJ9088600 |
Transport Information:
| HS Number | 2934999090 |
Application
Tinoridine Hydrochloride: A Nonsteroidal Anti-Inflammatory Agent with a Stabilizing Action on Lysosomes
Tinoridine hydrochloride (Y-3642 hydrochloride) is a nonsteroidal anti-inflammatory and analgesic agent, and also is a potent radical scavenger. It has been reported that tinoridine has a different mechanism of action than common nonsteroidal anti-inflammatory drugs (NSAIDs), which act by inhibiting the cyclooxygenase enzyme and thereby inhibit the synthesis of prostaglandins. The action is attributed to its bio-membrane stabilizing action particularly on the lysosomes which are related to cell or tissue damage at the time of inflammation through the release of hydrolytic enzymes. (The product is for research purpose only.)
References
- Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine. I
- Pharmacological investigations of 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine. II
- Antiinflammatory agents. XXVII. Inhibitory effects of antiinflammatory drugs on enzyme release from rabbit polymorphonuclear leukocyte lysosomes
- Hydroxyl radical scavenging action of tinoridine
- Rapid structural characterization of in vivo and in vitro metabolites of tinoridine using UHPLC-QTOF-MS/MS and in silico toxicological screening of its metabolites
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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