CAS RN: 165800-06-6 | Product Number: Z0031
Zoledronic Acid Monohydrate
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|Purity / Analysis Method||>98.0%(T)(HPLC)|
|Molecular Formula / Molecular Weight||C__5H__1__0N__2O__7P__2·H__2O = 290.11|
|Physical State (20 deg.C)||Solid|
|Condition to Avoid||Heat Sensitive|
|Related CAS RN||118072-93-8|
|Reaxys Registry Number||9667036|
|PubChem Substance ID||253662255|
|Merck Index (14)||10187|
|Melting Point||245 °C(dec.)|
|Solubility in water||Practically insoluble|
|Degree of solubility in water||7 g/l 25 °C|
|Solubility (insoluble in)||Ethanol,Methanol|
|Hazard Statements||H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
H361 : Suspected of damaging fertility or the unborn child.
|Precautionary Statements||P501 : Dispose of contents/ container to an approved waste disposal plant.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
1)Bisphosphonates: From bench to bedside
2)Computational insights into binding of bisphosphates to farnesyl pyrophosphate synthase
3)Novel insights into actions of bisphosphonates on bone: Differences in interactions with hydroxyapatite
4)Role of zoledronic acid in the prevention and treatment of osteoporosis
5)Emerging strategies and therapies for treatment of Paget’s disease of bone
6)The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy
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