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CAS RN: 551-15-5 | Product Number: L0269
Liquiritin
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Purity: >98.0%(HPLC)
Synonyms:
- Liquiritoside
- (S)-4',7-Dihydroxyflavanone 4'-β-D-glucoside
- 4-[(2S)-7-Hydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]phenyl β-D-Glucopyranoside
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
€162.00
|
1 | 5 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | L0269 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__2__2O__9 = 418.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 551-15-5 |
| Reaxys Registry Number | 61653 |
| PubChem Substance ID | 468592139 |
| MDL Number | MFCD00210526 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | -57.0 to -61.0 deg(C=0.5, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 212 °C |
| Maximum Absorption Wavelength | 364 nm (EtOH) |
GHS
Related Laws:
| RTECS# | DJ3095500 |
Transport Information:
| HS Number | 2938909090 |
Application
Liquiritin: A Flavonoid with Antidepressant, Neuroprotective, and Anti-Inflammatory Effects
Liquiritin, the 4'-O-glucoside of the liquiritigenin, is a flavonoid contained in Glycyrrhiza uralensis L., which is used as a sweetener and in traditional Chinese medicine. It has been reported that liquiritin shows pharmacological effects including antidepressant,1,2) neuroprotective3) and anti-Inflammatory4,5) effects. (The product is for research purpose only.)
References
- 1) Antidepressant-like effect of liquiritin from Glycyrrhiza uralensis in chronic variable stress induced depression model rats
- 2) Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice
- 3) Neuroprotective effect of liquiritin against focal cerebral ischemia/reperfusion in mice via its antioxidant and antiapoptosis properties
- 4) Anti-Inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver
- 5) Liquiritin from Glycyrrhiza uralensis Attenuating Rheumatoid Arthritis via Reducing Inflammation, Suppressing Angiogenesis, and Inhibiting MAPK Signaling Pathway
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