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CAS RN: 60142-96-3 | Product Number: G0318
Gabapentin
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Purity: >98.0%(GC)(T)
Synonyms:
- 1-(Aminomethyl)cyclohexaneacetic Acid
Product Documents:
| Size | Unit Price | Philadelphia, PA | Portland, OR | Japan* | Quantity |
|---|---|---|---|---|---|
| 5G |
$72.00
|
2 | 1 | ≥80 |
|
| 25G |
$219.00
|
6 | 1 | ≥60 |
|
* Items in stock locally ship in 1-2 business days. Items from Japan stock are able to ship from a US warehouse within 2 weeks. Please contact TCI for lead times on items not in stock. Excludes regulated items and items that ship on ice.
* To send your quote request for bulk quantities, please click on the "Request Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | G0318 |
Purity / Analysis Method 
|
>98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__9H__1__7NO__2 = 171.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 60142-96-3 |
| Reaxys Registry Number | 2359739 |
| PubChem Substance ID | 87560508 |
| SDBS (AIST Spectral DB) | 52390 |
| Merck Index (14) | 4319 |
| MDL Number | MFCD00865286 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
| Melting Point | 166 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P302 + P352 : IF ON SKIN: Wash with plenty of soap and water. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P362 : Take off contaminated clothing and wash before reuse. |
Related Laws:
| RTECS# | GU6496000 |
Transport Information:
| HS Number | 2922.49.8000 |
Application
Gabapentin: A γ-Aminobutyric Acid (GABA) Analog Anticonvulsant and Analgesic Agent
Gabapentin is a neurotransmitter γ-aminobutyric acid (GABA) [A0282] analog anticonvulsant and analgesic agent. Although the exact mechanism is unknown, gabapentin may reduce Ca2＋ currents into brain neurons through the binding to the α2δ subunit of voltage-dependent Ca2＋ channels and reduces the release of several monoamine neurotransmitters. Furthermore, gabapentin may increase the concentration and the rate of synthesis of GABA in brain. Although GABA does not cross the blood-brain barrier, gabapentin penetrates into the central nervous system. (The product is for research purpose only.)
References
- The novel anticonvulsant drug, gabapentin (Neurontin), binds to the α2δ subunit of a calcium channel
- A summary of mechanistic hypotheses of gabapentin pharmacology (a review)
- The mechanisms of action of Gabapentin (a review)
- Simultaneous high-performance liquid chromatographic analysis of pregabalin, gabapentin and vigabatrin in human serum by precolumn derivatization with o-phtaldialdehyde and fluorescence detection
- Development and application of a validated HPLC method for the determination of gabapentin and its major degradation impurity in drug products
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