Allyl 2,2,2-Trichloroacetimidate

Typical Procedure:
A solution of allyl 2,2,2-trichloroacetimidate (2 mmol) in cyclohexane (2 mL) and subsequently BF₃·Et₂O (20 µL) are added to a stirred solution of the carboxylic acid (1 mmol) in CH₂Cl₂ (1 mL). After stirring at room temperature overnight the precipitated trichloroacetamide is removed by filtration. The filtrate is washed with 5% NaHCO₃ aq., brine and then dried (Na₂SO₄). The solvent is evaporated under reduced pressure and the residue is purified by distillation or column chromatography using petroleum ether (40-60 °C) / EtOAc (9 : 1) as an eluent.