1,3-Bis[(2,2-dimethyl-1,3-dioxan-5-yl)oxy]-2-propanol (
1) can bind to hydrophobic molecules to make them hydrophilic after the deprotection of the acetonides. Owing to the lack of chiral carbons in
1, stereo isomers don’t form after the reaction, thus several applications using
1, such as the modification of water-indissoluble pharmaceuticals or Drug Delivery Systems (DDS), are expected. Hydroxy groups protected by acetonides can be easily deprotected in mild conditions, and the byproducts can be removed without difficulty.
