Pd-Catalyzed Amination of C-H Bonds Using F⁺

1-Fluoro-2,4,6-trimethylpyridinium triflate has been widely used as an electrophilic fluorinating agent in mild conditions. Yu et al. have reported Pd-catalyzed C–H amination reactions to form indolines using this compound as a resource of the two-electron oxidant, F⁺. It has been suggested that this reaction is caused by highly selective reductive elimination of an amino nucleophile from Pd(IV) species which are generated by F⁺ oxidation of amino-coordinated Pd(II). Since the substrate scope is broad, it seems to be suitable for the synthesis of building blocks including the indoline structure.