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CAS RN: 7240-38-2 | 产品编码: O0353

Oxacillin Sodium Salt Monohydrate


纯度/分析方法: >95.0%(T)
别名:
  • 苯唑西林钠盐 一水合物
文档:
1G
¥210.00
5   1   ≥20 
5G
¥805.00
2   2   13  
25G
¥2,190.00
4   1   13  
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Note:

This product has not been tested for potency and is guaranteed for chemical purity.

产品编码 O0353
纯度/分析方法 >95.0%(T)
分子式/分子量 C__1__9H__1__8N__3NaO__5S·H__2O = 441.44  
外观与形状(20°C) 固体
储存温度 0-10°C
储存在惰性气体下 存放于惰性气体之中
应避免的情况 湿气 (吸湿),加热
CAS RN 7240-38-2
相关CAS RN 66-79-5&1173-88-2
Reaxys-RN 4287093
PubChem物质ID 87560310
Merck Index (14) 6904
MDL编号

MFCD00167146

技术规格
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Volumetric Analysis) min. 95.0 %
Specific rotation [a]20/D +200.0 to +210.0 deg(C=1, H2O)(calcd.on anh.substance)
Water 3.5 to 5.0 %
物性(参考值)
熔点 188 °C(dec.)
比旋光度 [α]D 205° (C=1,H2O)
GHS
相关法规
新化学物质备案回执号 B1A232215175
运输信息
监管条件代码(*) Q类 (糖类,生物碱类,抗生素类,激素类)
应用
Oxacillin Sodium: A β-Lactamase-Resistant Penicillin

Oxacillin sodium, an isoxazolyl penicillin, is chemically synthesized from 6-APA [A0800] and [M2996]. Oxacillin has activity against Gram-positive bacteria, but less activity against Gram-negative bacteria, the same as penicillin G [P1770] [P1772]. It acts as a competitive inhibitor of the enzyme transpeptidase, which is needed by bacteria to make their cell walls. Meanwhile, oxacillin, cloxacillin [C2244] and methicillin are resistant to the enzymes (β-lactamases) which produced by bacteria that destroy β-lactam antibiotics like penicillins and cephalosporins, due to theirs large side-chain, which does not allow the β-lactamases to bind. However, with the widespread use of oxacillin, antibiotic-resistant strains called oxacillin-resistant Staphylococcus aureus (ORSA) have become increasingly prevalent worldwide.

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