轻松扫码查看产品文档 | TCIMAIL No.197 已上新 | TCI试剂——品质可靠,值得信赖
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CAS RN: 82419-36-1 | 产品编码: O0403
Ofloxacin

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* TCI会经常复审储藏条件以对其进行优化,请以在线目录为准,敬请留意。
* 更多信息,请联系营业部:021-67121386 / Sales-CN@TCIchemicals.com 。任何货期、规格或包装方面的需求,请联系我们 。
* 无具体发货日期的情况,如:显示“8个工作日后发货”,将在您订购日起的8个工作日后发货。
* 我们将以最优方式从上海/天津两大仓库发货。国内库存不足,需两周左右向日本总部调货。
* 对于可分装产品,11:30前的订单,当天发货;11:30后的订单,隔天发货。
* 如需大包装,请点击“大包装询价”按钮(对于某些产品我们无法提供大包装)。
* TCI会经常复审储藏条件以对其进行优化,请以在线目录为准,敬请留意。
* 更多信息,请联系营业部:021-67121386 / Sales-CN@TCIchemicals.com 。任何货期、规格或包装方面的需求,请联系我们 。
技术规格
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
物性(参考值)
熔点 | 263 °C |
最大吸收波长 | 326(H2O) nm |
GHS
信号词 | 警告 |
危险性说明 | H303 : 吞咽可能有害。 |
防范说明 | P312 : 如感觉不适,呼叫急救中心/医生。 |
相关法规
RTECS# | UU8815500 |
运输信息
监管条件代码(*) |
应用
Ofloxacin: A Synthetic Fluoroquinolone Antimicrobial, Ofloxacin
Ofloxacin is a synthetic fluoroquinolone antimicrobial structurally related to nalidixic acid [N0490]. Ofloxacin has broad-spectrum bactericidal activity against most Gram-negative bacteria, many Gram-positive bacteria and some anaerobes. The mechanism of action of ofloxacin (and other fluoroquinolone) involves inhibition of bacterial topoisomerase IV and DNA gyrase (topoisomerases II), enzymes required for DNA replication, transcription, repair and recombination. The active S-(-)-enantiomer of ofloxacin is levofloxacin [L0193]. (The product is for research purpose only.)
References
- Ofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use
- Quinolones in 2005: an update (a review)
- Moxifloxacin [M2479], ofloxacin, sparfloxacin [S0896], and ciprofloxacin [C2227, C2510] against Mycobacterium tuberculosis: evaluation of in vitro and pharmacodynamic indices that best predict in vivo efficacy
- Synthesis and antibacterial activities of optically active ofloxacin
- Direct determination of four fluoroquinolones, enoxacin [E0762], norfloxacin [N0817], ofloxacin, and ciprofloxacin [C2227, C2510], in pharmaceuticals and blood serum by HPLC
- Determination of ofloxacin, norfloxacin [N0817], and ciprofloxacin [C2227, C2510] in sewage by selective solid-phase extraction, liquid chromatography with fluorescence detection, and liquid chromatography-tandem mass spectrometry
应用
Studies of the Antimicrobial Activity and the Determination of Ofloxacin
References
- Quinolones in 2005: an update
- In vitro and in vivo activity of DL-8280, a new oxazine derivative
- Fourth generation fluoroquinolones: New weapons in the arsenal of ophthalmic antibiotics
- Direct determination of four fluoroquinolones, enoxacin, norfloxacin, ofloxacin, and ciprofloxacin, in pharmaceuticals and blood serum by HPLC
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