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Published TCIMAIL newest issue No.201
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CAS RN: 23930-19-0 | Product Number: A3644
Alphaxalone
×
Purity: >98.0%(HPLC)
Synonyms:
- Alfaxalone
- 3α-Hydroxy-5α-pregnane-11,20-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
125,00 €
|
1 | 25 |
|
|
| 25MG |
435,00 €
|
Contact Us | ≥40 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | A3644 |
Purity / Analysis Method 
|
>98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__1H__3__2O__3 = 332.48 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 23930-19-0 |
| Reaxys Registry Number | 3217240 |
| MDL Number | MFCD00083468 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 168.0 to 172.0 °C |
| Specific rotation | +105 to +115 deg(C=1, CHCl3) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 170 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | TU4157800 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2914409090 |
Application
Alfaxane: A Neurosteroid Action on GABAA Receptors
Alfaxane is a neurosteroid and general anesthetic with minimal cardiorespiratory effects and is used in veterinary practice. There are reports that alfaxalone acts as a positive allosteric modulator on GABAA receptors and, at high concentrations, as a direct agonist of the GABAA receptor. (The product is for research purpose only.)
References
- A review of the pharmacology and clinical application of alfaxalone in cats
- Clinical review of the pharmacological and anaesthetic effects of alfaxalone in dogs
- Structural basis of neurosteroid anesthetic action on GABAA receptors
Product Documents (Note: Some products will not have analytical charts available.)
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