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CAS RN: 25122-46-7 | Product Number: C2612

Clobetasol 17-Propionate


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 21-Chloro-9α-fluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
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Product Number C2612
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__2__5H__3__2ClFO__5 = 466.97  
Physical State (20 deg.C) Solid
Storage Temperature 0-10°C
Condition to Avoid Heat Sensitive
CAS RN 25122-46-7
Reaxys Registry Number 4769432
PubChem Substance ID 160870993
Merck Index (14) 2363
MDL Number

MFCD00058499

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Argentmetric Titration) min. 98.0 %
Melting point 196.0 to 200.0 °C
Specific rotation [a]20/D +99.0 to +103.0 deg(C=1,Dioxane)
Properties (reference)
Melting Point 198 °C
Specific Rotation 101° (C=1,Dioxane)
Solubility (soluble in) Dioxane
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H315 : Causes skin irritation.
H319 : Causes serious eye irritation.
Precautionary Statements P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P302 + P352 : IF ON SKIN: Wash with plenty of water.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P362 + P364 : Take off contaminated clothing and wash it before reuse.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
Related Laws:
EC Number 246-634-3
RTECS# TU3725000
Transport Information:
HS Number 2937220000
Application
Studies on Nanoparticles with Clobetasol Propionate
References

Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization

F. Q. Hu, H. Yuan, H. H. Zhang, M. Fang, Int. J. Pharm. 2002, 239, 121

Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin

T. Şenyiğit, F. Sonvico, S. Barbieri, Ö. Özer, P. Santi, P. Colombo, J. Controlled Release 2010, 142, 368


PubMed Literature


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