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CAS RN: 169590-42-5 | Product Number: C2816

Celecoxib


Purity: >98.0%(T)(HPLC)
Synonyms:
  • 5-(4-Methylphenyl)-1-(4-sulfamoylphenyl)-3-(trifluoromethyl)pyrazole
  • 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Documents:
200MG
€25.00
4   ≥20 
1G
€81.00
10   ≥20 

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Product Number C2816
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__7H__1__4F__3N__3O__2S = 381.37  
Physical State (20 deg.C) Solid
CAS RN 169590-42-5
Reaxys Registry Number 7662430
PubChem Substance ID 253660758
Merck Index (14) 1956
MDL Number

MFCD00941298

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 161.0 to 165.0 °C
Properties (reference)
Melting Point 163 °C
Solubility in water Insoluble
Solubility (very soluble in) Methanol
Solubility (soluble in) Ethanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H361 : Suspected of damaging fertility or the unborn child.
H373 : May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws: / Compliance with laws, Regulations
RTECS# DB2944937
Transport Information:
HS Number 2935909099
Application
Celecoxib: A Selective Cyclo-Oxygenase-2 (COX-2) Inhibitor

Celecoxib (SC-58635), a nonsteroidal anti-inflammatory drug (NSAID), is a cyclo-oxygenase (COX) inhibitor that exhibits relative selectivity for COX-2 over COX-1 in vitro and in vivo. In theory, a drug such as celecoxib that selectively inhibited COX-2 might block inflammation, pain, and fever produced by prostaglandins while reducing the side effects (gastric erosions and ulcers) associated with inhibition of COX-1. In addition, celecoxib is reported that has anticancer properties.

References


PubMed Literature


TCIMAIL
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