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Published TCIMAIL newest issue No.201
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CAS RN: 970-74-1 | Product Number: E1084
(-)-Epigallocatechin
×
Purity: >98.0%(GC)
Synonyms:
- (-)-cis-3,3',4',5,5',7-Hexahydroxyflavane
- (-)-cis-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
€ 74,00
|
4 | ≥80 |
|
|
| 50MG |
€ 252,00
|
2 | ≥100 |
|
* Stock available in Belgium: Shipment on the same day
* Stock available in Japan: Please check the Shipping Simulation for estimated shipments. (excludes regulated items and dry ice shipments)
| Product Number | E1084 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__5H__1__4O__7 = 306.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 970-74-1 |
| Reaxys Registry Number | 94057 |
| PubChem Substance ID | 253662585 |
| MDL Number | MFCD00075939 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 98.0 % |
| Specific rotation [a]20/D | -48.0 to -51.0 deg(C=0.5, Acetone) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 210 °C(dec.) |
| Specific Rotation | -50° (C=0.5,Acetone) |
| Maximum Absorption Wavelength | 278 nm (MeOH) |
GHS
Related Laws:
| RTECS# | KB5100000 |
Transport Information:
| HS Number | 2932990090 |
Application
Research on gene transfer methods / Enhancement of lipofection efficiency
(-)-Epigallocatechin has been reported to enhance the transfection efficiency in Colon26 and HepG2 cells.1)
Reference
- 1) Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation
- 1) The Inhibitory Effects of Catechins on Biofilm Formation by the Periodontopathogenic Bacterium, Eikenella corrodens
- 1) Inhibitory effect of green tea catechins on cysteine proteinases in Porphyromonas gingivalis
- 2) Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids
- Metabolism of green tea catechins: an overview
- Plant polyphenols: How to translate their in vitro antioxidant actions to in vivo conditions (a review)
- Green Tea: Nature's Defense against Malignancies (a review)
- Flavanols from green tea and phenolic acids from coffee: Critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages (a review)
- Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities (a review)
Application
Biofilm research
(-)-Epigallocatechin was reported to inhibit biofilm formation by periodontopathoginic bacterium, Eikenella corrodents.1)
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
Application
Gingipain inhibitor
(-)-Epigallocatechin has been reported to inhibit against Arg-gingipain (Rgp) in Porphyromonas gingivalis (IC50 = 20 μM).1) The compound was also shown to inhibit Lys-gingipain (Kgp), although weaker than Rgp.2)
(The product is for research purpose only.)
(The product is for research purpose only.)
References
Application
(-)-Epigallocatechin: One of the Major Components of Green Tea with Antioxidative, Anti-Inflammatory and Anti-Cancerous Properties
(-)-Epigallocatechin (EGC), a catechin derivative, is one of the major components of green tea. It has been demonstrated strong antioxidative, anti-inflammatory and anti-cancerous properties.
References
PubMed Literature
Product Articles
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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