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Peptide Chemistry

Peptides are chains of amino acid residues connected via amide linkages. Peptides composed up to 10 amino acid residues are referred to small peptides, while those with up to 100 residues are known as (poly)peptides. A peptide moiety forms prime constituent of not only proteins but also aspartame, an artificial non-saccharide sweetener. Peptides serve various functions in organisms, especially the peptide hormones which play important roles in signal transductions. Some synthetic peptides can also be used as reagents for biochemical research and in pharmacy.1)
Since the number of naturally occurring bioactive peptides is limited and the genes corresponding to the peptides are usually unknown, peptide synthesis enables the further research for functional analysis of the peptides. To date, peptides with several dozen of residues can be obtained by solid phase peptide synthesis. Peptides with a small number of residues can also be prepared in a large scale by liquid phase synthesis. This section shows reagents used in peptide synthesis.


References

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Alanine Derivatives [Unnatural Amino Acid Derivatives] Alicyclic Amino Acids [Unnatural Amino Acid Derivatives] Aromatic Amino Acids [Unnatural Amino Acid Derivatives] Cysteine Derivatives [Unnatural Amino Acid Derivatives] DAB (2,4-Diaminobutyric Acid) [Unnatural Amino Acid Derivatives] DAP (2,3-Diaminopropionic Acid) [Unnatural Amino Acid Derivatives] Glutamic Acid Derivatives [Unnatural Amino Acid Derivatives] Glycine Derivatives [Unnatural Amino Acid Derivatives] Homo-Amino Acids [Unnatural Amino Acid Derivatives] Isoleucine Derivatives [Unnatural Amino Acid Derivatives] Leucine Derivatives [Unnatural Amino Acid Derivatives] Linear Core Amino Acids [Unnatural Amino Acid Derivatives] Methionine Derivatives [Unnatural Amino Acid Derivatives] N-Methyl Amino Acids [Unnatural Amino Acid Derivatives] Norleucine Derivatives [Unnatural Amino Acid Derivatives] Norvaline Derivatives [Unnatural Amino Acid Derivatives] Ornithine Derivatives [Unnatural Amino Acid Derivatives] Penicillamine Derivatives [Unnatural Amino Acid Derivatives] Phenylalanine Derivatives [Unnatural Amino Acid Derivatives] Phenylglycine Derivatives [Unnatural Amino Acid Derivatives] Proline Derivatives [Unnatural Amino Acid Derivatives] Serine Derivatives [Unnatural Amino Acid Derivatives] Threonine Derivatives [Unnatural Amino Acid Derivatives] Tryptophan Derivatives [Unnatural Amino Acid Derivatives] Tyrosine Derivatives [Unnatural Amino Acid Derivatives]
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