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CAS RN: 320-67-2 | Product Number: A2033

5-Azacytidine


Purity: >98.0%(T)
Synonyms:
  • 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
  • Ladakamycin
Documents:
100MG
€ 28,00
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1G
€ 143,00
1   ≥20 

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Product Number A2033
Purity / Analysis Method >98.0%(T)
Molecular Formula / Molecular Weight C__8H__1__2N__4O__5 = 244.21  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Light Sensitive,Heat Sensitive
CAS RN 320-67-2
Reaxys Registry Number 620461
PubChem Substance ID 87559665
Merck Index (14) 887
MDL Number

MFCD00006539

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 97.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Properties (reference)
Melting Point 216 °C(dec.)
Solubility in water Soluble
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H302 : Harmful if swallowed.
H340 : May cause genetic defects.
H350 : May cause cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
Related Laws:
EC Number 206-280-2
RTECS# XZ3017500
Transport Information:
HS Number 2934999090
Application
An Inhibitor of DNA Methylation

The cytidine analogs 5-azacytidine and 5-aza-2'-deoxycytidine [A2232] are inhibitors of DNA methyltransferases (DNMTs) which catalyze the transfer of a methyl group to DNA. DNA methylation is an epigenetic factor and plays an important role in regulating gene expression. 5-Azacytidine and 5-aza-2'-deoxycytidine are the currently most advanced agents for epigenetic cancer therapies. (The product is for research purpose only.)

References


Application
Aminophylline: A Water Soluble Theophylline

References


PubMed Literature


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